Collection, Processing, and Storage
CBR's CellAdvantage® System Saves More Cord Blood Stem Cells for Your Family
CBR is dedicated to collecting the highest volume of cord blood for families because having more stem cells for treatment can improve medical outcomes if the cells are ever needed for transplant.
With CBR's exclusive CellAdvantage® system, every detail of CBR's process has been diligently developed, resulting in the best technology available for collecting, processing, and storing a newborn's stem cells. The combination of CBR's new collection bag, proprietary dry heparin anticoagulant (which helps preserve the cord blood during transport to the lab), and superior processing technology improves our ability to save every stem cell possible for your family.
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| ActiveFlo chamber is designed to increase the amount of cord blood collected | CBR's heparin saves more stem cells from the blood | ||
STEP 1: Safe and Easy Cord Blood Collection
Your CBR CellAdvantage Collection Kit, built to FDA and OSHA standards, contains everything your healthcare provider will need to easily and safely collect your newborn's stem cells following vaginal or cesarean birth. The collection takes only a few minutes and poses no risk to you or your baby. Your normal birthing process will not change.
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CBR's CellAdvantage Collection Bag—Designed to Collect More Cord Blood
CBR's new and innovative cord blood collection bag, which is 100% sterile, is the only active collection system available. This technology is exclusive to CBR and features our unique ActiveFlo™ chamber, which is designed to give healthcare providers control to collect the highest volume of cord blood. And it provides clear visibility of blood flow to remove the risk of ending the collection too soon. Collecting more blood means we can store more stem cells. -
CBR's Unique Heparin Helps Ensure You Get the Most Cells Possible
CBR's proprietary dry heparin anticoagulant improves our ability to recover every stem cell possible, regardless of collection volume. In family banking, where blood collection volumes and delivery times to labs vary greatly, heparin has many advantages over other commonly used anticoagulants such as liquid CPD.
STEP 2: FDA-Cleared Processing Technology
Cord blood is processed to remove excess red blood cells in order to store a higher concentration of stem cells and to reduce risks when used in treatment. CBR uses a FDA-cleared cord blood processing technology called the AXP™AutoXpress Platform, which was developed with Thermogenesis® and is distributed by GE® Healthcare. When combined with CBR's proprietary dry heparin, this automated, computer-controlled processing system delivers the highest published cell recovery rate in the industry—99%.1 Other processing methods like Sepax® and Hespan® have been shown to recover only 81% of cells.2,3
STEP 3: Storage—Protecting Your Investment
From collection to storage, CBR takes every step possible to ensure the long-term safety and viability of your newborn's stem cells. According to the New York State Health Department guidelines for cord blood banking, cord blood stem cells can be stored indefinitely under the proper conditions.4
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FDA-Cleared, Seamless Cryostorage Bags
CBR uses only FDA-cleared, seamless storage bags. Created with blow-molded technology, seamless bags are designed to be inherently stronger than first-generation seamed bags that may trap cells or cause potential points of weakness. Bag strength is critical in cryostorage where samples are stored at an extreme temperature for a long period. CBR stores cord blood in four segments to allow for testing and the possibility of multiple uses. Each storage bag is placed in a hermetically sealed overwrap envelope to protect your baby's cord blood from exposure to other samples.

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how CBR CellAdvantage saves more cord blood stem cells for your family. |
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References:
1. Rosenthal J, Brown H, Harris D. Stem Cell Recovery Following Implementation of an Automated Cord Blood Processing System in a High Volume Laboratory. Biol Blood Marrow Transplant. 2008; 14(2):S42. 2. Papassavas AC, Goika V, Chatzistamatiou T, et al. A strategy of splitting individual high volume cord blood units into two half subunits prior to processing increases the recovery of cells and facilitates ex vivo expansion of the infused haematopoietic progenitor cells in adults. Int Jnl Lab Hem. 2007;1-9 3. Kurtzberg J, Cairo MS, Fraser JK, et al. Results of the Cord Blood Transplantation (COBLT) Study unrelated donor banking program. Transfusion. 2005;45:842-855 4. Linden JV, Preti RA, Dracker, R. New York state guidelines for cord blood banking. Journal of Hematotherapy. 1997;6:535-41.
AXP™ and Thermogenesis® are the registered trademarks of Thermogenesis Corporation. GE® is the registered trademark of General Electric Company. Sepax® is the registered trademark of Biosafe S.A. Corporation Switzerland. Hespan® is the registered trademark of B. Braun.



