Stem Cell Information and Developments

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CBR’s newsletter Stem Cells: Beyond the Microscope provides information about the latest in newborn stem cell medical developments and emerging trials and therapies. Browse the archive below for a look at past, present, and potential future advancements in stem cell medicine.

July is Cord Blood Awareness Month
July 2013 – July has been designated Cord Blood Awareness Month by the National Health Information Center. Now more than ever is the time to educate your staff, colleagues, and expecting parents about the therapeutic value of umbilical cord blood stem cells and the options for saving or donating them.

Newborn Possibilities Program: A Commitment to Advancing Cord Blood Stem Cell Science
April 2013 – Transplants using stem cells found in cord blood have become an established therapy over the past 20 years, with more than 25,000 cord blood transplants already conducted worldwide to treat specific cancers, and blood, metabolic, and immune disorders. Cord blood stem cells are also being evaluated in a wide range of regenerative medicine clinical trials with promising preliminary results. Cord Blood Registry® established the Newborn Possibilities Program® in 1997 to be a catalyst for advancing newborn stem cell medicine and science. The program offers free cord blood stem cell processing and storage for five years to families with an immediate need for a stem cell transplant or to babies diagnosed prenatally or born with specific risk factors for neurological impairment.

New Study May Help Explain How Mesenchymal Stem Cells Improve Symptoms of Autoimmune Diseases
June 2012 – Mesenchymal stem cells (MSCs) are showing potential in research for treatment of autoimmune conditions, but the exact mechanism for their anti-inflammatory effect is not known. A recent study published in Cell Stem Cell explores one immune pathway involving a cell surface protein called FAS ligand. The study showed that mice injected with bonemarrow- derived MSCs lacking the cell surface protein did not show the anti-inflammatory effect observed when MSCs with the protein were injected. These results help advance a better understanding of how MSCs modulate the immune system to advance research on stem cell-based therapies for many diseases.

From Bench to Bedside: How Educating Families about Cord Banking Can Advance Regenerative Medicine
May 2012 – Regenerative medicine research with cord blood-derived newborn stem cells is advancing quickly, with clinical trials emerging at a rapid rate. Eligibility for these trials is dependent upon a choice made at birth; it generally requires that patients have preserved their own (autologous) cord blood stem cells.

New Data Suggests Type of Anticoagulant Affects Cord Blood Viability During Transport 
January 2012 – Umbilical cord blood (UCB) is a valuable source of hematopoietic stem cells for transplantation and regenerative medicine applications, but few studies have evaluated the optimal anticoagulant for collection and transportation of cord blood. A poster presented at the American Society of Hematology (ASH) Annual Meeting compared the cell characteristics of cord blood units preserved for transportation with one of two commonly used anticoagulants.

First Use of Cord Tissue in Humans 
September 2011 – The first reported human clinical use of cord tissue mesenchymal stem cells revealed them to be feasible, safe, and effective in treating a potentially fatal complication of hematopoietic stem cell transplantation.

Designated Treatment Program Expanded to Include Cord Tissue Storage
August 2011 – CBR announced the expansion of its medical need-based initiative, the Designated Treatment Program, to include free umbilical cord tissue storage for qualifying families.

July is Cord Blood Awareness Month
June 2011 – Educate yourself and your family about the therapeutic value of cord blood stem cells in transplant and regenerative medicine and available banking options.

Long-Term Storage of Cord Blood: No “Expiration Date” for Newborn Stem Cells
April 2011 – Newborn umbilical cord blood holds its value. A current study validates the lasting utility of cord blood stem cells after long-term cryogenic storage.

Ask the Expert: Dr. Rogers on the Regenerative Potential of Newborn Stem Cells
March 2011 – Dr. Ian Rogers, a leading stem cell researcher, provides insight on the current state of regenerative medicine research with newborn stem cells.

New Medical Research Focused on Cord Blood Stem Cells to Help Treat Brain Injury
February 2011 – Groundbreaking clinical trial explores the potential of stem cell-based therapies to help initiate repair and induce healing of damaged brain tissue in children.

Health Policy Everyone Can Support: Educating All Expectant Parents about Cord Blood Stem Cells
May 2010 – To date, 20 states have passed laws that require or encourage healthcare providers to offer patients better information on cord blood stem cells and the options for preserving them.

Advances with Mesenchymal Stem Cells: New Frontiers in Cell Therapy
February 2010 – As advances in stem cell science accelerate, different cell types are being studied for a growing number of potential therapeutic applications.

Cord Blood May Help Repair Children’s Heart Defects
December 2008 – Cardiologists from the University Hospital of Munich report they are about five years away from transplanting new heart valves into children born with heart defects, made from the children's own cord blood.

American Heart Association (AHA) Issues First Guidelines on Stroke in Infants and Children: Cord Blood Stem Cells Being Researched as Treatment Option

October 2008 – Physicians have recently been issued the AHA’s first guidelines for diagnosing and treating stroke in infants and children, the sixth leading cause of death among them.

Neurological Disorders: A Focus on Cord Blood Stem Cells as a Potential Treatment Option
June 2008 – Scientists are pursuing research to gain a better understanding of the human nervous system in order to find new breakthroughs –stem cell therapy being one of the most promising of all the therapeutic options.

Cord Blood Stem Cells and Cardiovascular Disease
January 2008 – Although heart disease impacts an older population, heart ailments also strike the very young. Researchers are exploring potential therapies using stem cell sources to repair or replace damage.

Cord Blood Stem Cell Expansion: Increasing the Yield of a Valuable Resource
December 2007 – Researchers are developing methods to stimulate the division of cord blood stem cells to increase the total number of stem cells and allow for multiple uses.

Cord Blood Stem Cells: A Promising Future in Orthopedics
September 2007 – The National Institutes of Health (NIH) will be advancing its research of non-embryonic, pluripotent stem cells after reviewing exciting advancements seen in orthopedics and sports medicine.

Pluripotency of Stem Cells: An Overview
May 2007 – Cord blood stem cells have vast medical potential and have been used in treatments for more than 20 years. Pluripotency refers to a stem cell's ability to transform into any fetal or adult cell type.

A Comparison of Stem Cell Sources: Key Differences in Therapeutic Viability and Effectiveness
March 2007 – Cord blood stem cells have distinct clinical benefits over other primary, proven sources of non-controversial embryonic-like stem cells for scientific study or therapeutic use.